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Acknowledgements This work was supported by grants from the Enterprise Joint Fund Project of Hunan Provincial Natural Science Foundation, 2024JJ9097

Following the epithelial tubular structure of Bowmans capsule, the filtrate enters the proximal tubule which resides within the cortical tissue of the kidney

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However, there is no uniform pattern that can dichotomously distinguish hypervirulent strains from carrier strains, which indicates that meningococcal pathogenicity is complex and multifactorial