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328 Although GNMT is considered a novel therapeutic target for DKD, treatment strategies targeting GNMT may need to account for individual differences, such as genetic polymorphisms, disease stage, and comorbidities, all of which could influence treatment outcomes

Tirzepatide is FDA-approved as Mounjaro for type 2 diabetes (2022) and as Zepbound for chronic weight management (2023) and for moderate-to-severe obstructive sleep apnea (2024), and it is EMA-approved as well

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