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Manufacturers must conduct studies proving their generic versions are bioequivalent to the brand-name product, then submit these for FDA approval
While glycemic index/load concepts may help some individuals, the American Diabetes Association notes that overall dietary patterns matter more than focusing solely on glycemic index
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Furthermore, validation has been achieved with small molecules such as GSK137647A, which activates the Free Fatty Acid Receptor 4 (FFAR4, also known as GPR120), and with Sinigrin, an agonist of the Bitter Taste Receptor 38 (TAS2R38)
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