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The B12 injection is ordered by a licensed MD, prepared and administered by a registered nurse, and takes 10 minutes

Temporary dose reduction during illness or significant life stress is reasonable, with resumption of escalation once circumstances normalize

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89 Additionally, the binding affinity between protein disulfide-isomerase (P4HB) and prostaglandin G/H synthase 2 (PTGS2) is enhanced by lactylation of P4HB at K311, subsequently leading to SH3-domain-containing GRB2-like protein B1 (SH3GLB1)-mediated mtROS accumulation and coiled-coil domain-containing protein 2 (NDP52)-induced mitophagy

It is not approved by the FDA for clinical use