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These frameworks consider factors such as hormone responses (including insulin, GLP-1, and leptin), individual differences in hunger and fullness control, and brain reward processing
YLC, BGO, SS, NMJ and HC contributed to the writing of the main manuscript text, and YLC prepared Figures 18 and Tables 1, 2
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A therapy that appeals to both male and female physiology, while staying independent of hormone levels, offers a level of versatility unmatched in many modern interventions
The oxidation of DA aggravates the dopaminergic cell death induced by MPP + challenge [103], while DA depletion can remarkably alleviate dopaminergic neuronal degeneration caused by mitochondrial complex I inhibitors [104]
Together, these drugs were intended to create a potent appetite-suppressing effect, helping patients achieve significant weight loss
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