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Hypoglycemia risk in non-diabetics: This appears to remain low with retatrutide, but glucagon's role in glucose regulation warrants close monitoring

Here is what the clinical evidence shows: Key sources: Weight loss is typically fastest in the first 36 months and then plateaus

Other medications that can increase the risk of hypoglycemia or ketoacidosis: avoid taking Invokana with other medications that can increase the risk of hypoglycemia (low blood sugar) or ketoacidosis (a serious condition caused by too much acid in your body)

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