36 Lanifibranor achieved the primary endpoint with a statistically significant reduction in steatohepatitis evaluated by the steatosis activity fibrosis histological score without worsening fibrosis
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In 12 weeks, study participants who lost weight with GLP-1s or gastric bypass surgeries noted they saw at least a 20% increase in facial volume, elasticity, firmness and hydration, while experiencing a major decrease in wrinkles
10.1186/s12974-017-0839-0 16 CarnielB
Naltrexone, an opioid antagonist prescribed to treat alcoholism, has been shown to reduce the palatability of alcohol, essentially making booze taste bad (or worse)