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The neuropsychopharmacology of acetyl-L-carnitine (LAC): basic, translational and [PMID: 38169018] Laboratory literature summary: The neuropsychopharmacology of acetyl-L-carnitine (LAC): basic, translational and investigational implications

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A 2015 study by Huang and colleagues in Drug Design, Development and Therapy used a rat alkali-burn model (n=10 per group) and HUVECs treated with BPC-157 at 200800 ng/mL, reporting accelerated wound closure with enhanced granulation tissue, reepithelialization, and dermal remodeling by day 18, alongside increased endothelial migration and vascular tube formation in vitro via ERK1/2 phosphorylation though the abstract does not report numeric % wound closure or p-values

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Gastroparesis-like symptoms associated with Ozempic, Wegovy, Mounjaro and other GLP-1 receptor agonists may resolve after stopping use of the medications

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Conclusions GLP1-RA reduce the risk of MACE by 14% in eight CVOTs with 60,080 patients with T2DM over a period ranging from 1.3 to 5.4 years

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