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A significant presence of a GSTP1-1 allelic variant (the GSTP1*C allelic variant) was found in late-onset AD patients 52

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In the absence of Keap1, Nrf2 is constitutively stabilized, and the expression of Nrf2 target genes is maintained at high levels (Wakabayashi et al., 2003)

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Search popularity, however, is not the same as clinical validation