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2017 Cell study (PMID: 28340339) used 5 mg/kg body weight administered via intraperitoneal injection three times per week

Medvidovic-Grubisic et al., 2017), stroke (Vukojevic et al., 2020), and spinal cord injury (Perovic et al., 2019))

Glutathione is also critical for energy production

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a Synergy 2 (BioTek)

This indicates that while higher doses may have some impact on kidney function, this effect is reversible and does not occur at lower, more commonly used doses