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This proactive approachunderstanding which compounds may offer benefitsis just as important as knowing which ones don't pose a threat
1), and the first GLP-1 analogue brought into clinical development was liraglutide, a once-daily injection
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In cases requiring more intensive glucose control, insulin therapy remains an effective option, though it requires more frequent monitoring and carries a risk of hypoglycaemia and weight gain
A modest increase in heart rate was also observed, a signal seen with other incretin-based weight-loss agents
One study found that people regained about two-thirds of the weight they lost within a year of stopping semaglutide
