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The results generally show reduced neurological deficit scores and faster behavioral recovery in treated animals

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Oxidative damage primarily affects the lysine residue, forming oxidized lysine derivatives that retain partial NF-B inhibition but with altered potency

Moreover, in studies it appears to support angiogenesis and tendon cell models

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In cardiac models, Bock-Marquette et al., Nature 2004 reported that T4 activates integrin-linked kinase and Akt signalling, promoting cardiomyocyte survival, migration and improved function after coronary ligation in mice