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Since AOMs are indicated in combination with lifestyle interventions, all participants received dietary and physical activity counseling, aiming to achieve a 500-kcal deficit per day and 150 minutes of physical activity per week

Semaglutide has two amino acid substitutions compared to human GLP-1 (Aib(8), Arg(34)) and is derivatized at lysine 26

Reduces Arterial Stiffness Arterial stiffness is a key factor in hypertension

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