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From a clinical perspective, unexplained loss of glycemic control or weight loss plateau after previously good response may suggest medication issues, though this requires careful differential diagnosis

I wanted to highlight a couple more things that I thought were also very important

Patients inflammatory markers improve

By meta-analysis of the individual cardiovascular endpoints, significant improvements were established for all of the following: myocardial infarction, stroke, cardiovascular mortality, all-cause mortality and hospitalisation for heart failure

The unit markings on the syringe are simply a more readable way to measure tiny volumes

doi: 10.1016/S0140-6736(18)32260-8 112 FrasJPDaviesMJRosenstockJPrez ManghiFCFernndez LandLBergmanBKet al