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Like many therapeutic peptides, it may require daily (or near-daily) administration, as in the previously referenced mouse and rabbit studies.12 17 Moreover, as a preventive or a drug for managing chronic health conditions, treatment ought to be ongoing and may involve periodic breaks in dosing (cycling), which is also common with many therapeutic peptides

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Clinically meaningful responses in insulin-resistant patients typically include a reduction in fasting insulin of 20-40% and an improvement in HOMA-IR within 8-12 weeks at therapeutic doses, though individual variability is wide [1]

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