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The authors hypothesized that the medication may trigger immune responses, as the inflammation resolved after intralesional hyaluronidase administration
Naiki T, Naiki-Ito A, Asamoto M, Kawai N, Tozawa K, Etani T, et al
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( Reference Martinov, Vitvitsky and Mosharov 39 ) , in a mathematical modelling study of SAM metabolism in the liver, stated that when SAM levels are low, priority for this substrate goes to transmethylation reactions, promoting reduction of the trans-sulfuration pathway
