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Other common symptoms may include myalgia, muscle weakness, headache, sleep disorders, neurocognitive and psychiatric manifestations, anorexia or autonomic manifestations (orthostatic intolerance, cardiovascular, respiratory, gastro-intestinal, or gastro-urinary) (16) Compared with influenza, sequelae of L-C19 were higher in terms of anxiety and mood disorders, insomnia, and dementia (17)

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Although GLP-1RAs can reduce body weight by 15%25% in controlled settings, real-world adherence is limited, and nearly 70% of patients experience weight regain after discontinuation, raising the risk of long-term pharmacological dependence ( Looking ahead, the future of GLP-1based therapy will depend on addressing safety concerns, improving long-term adherence, and expanding clinical indications

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