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This preclinical study shows that GSH supplementation increased brain Glutathione levels, reduced oxidative damage, and improved memory deficits in mice.
Generally, the synthesis of melanin is a complex process, with a multitude of genes influencing its production, such as tyrosinase-related protein 1 ( TRP-1 ), glycogen synthase kinase-3 beta ( GSK3 ), -catenin , cyclic adenosine monophosphate ( cAMP ), cAMP-response element binding protein ( CREB ), and solute carrier family 7 member 11 ( SLC7A11 ) [93, 185, 228]
Dihydroartemisinin (DHA) induces oxidative stress in cancer cells by increasing intracellular ROS
This mechanistic difference suggests they may have complementary effects when studied in laboratory settings, potentially affecting different aspects of the tissue repair process
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