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Importance of neonatal FcR in regulating the serum half-life of therapeutic proteins containing the Fc domain of human IgG1: a comparative study of the affinity of monoclonal antibodies and Fc-fusion proteins to human neonatal FcR
GLP-1 modulates glucose homeostasis via pleiotropic actions [15, 16], including stimulation of insulin secretion, suppression of glucagon release [17], slowing of gastric emptying [18] and inhibition of appetite [19]
Semaglutide on the other hand displays limited efficacy in crossing the BBB, but despite this fact it was proven to access the brainstem, septal nucleus and hypothalamus [42]
10.1161/ATVBAHA.108.174359 Arterioscler Thromb Vasc Biol
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