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Medication is one piece of the picture

And melatonin itself may have anti-aging properties independent of its antioxidant effects research has suggested roles in mitochondrial function, DNA repair, and even telomere maintenance

Haines I, Andreeff M , Mertelsmann R, Chaganti R, Nahmias N, Clarkson BD

Commentary: Validation of the Pittsburgh Esophageal Perforation Severity Score: Further Impetus for a Prospective Study

(2017) Environmental cystine drives glutamine anaplerosis and sensitizes cancer cells to glutaminase inhibition