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10.1021/acs.jmedchem.3c00320 18 CoskunT.SloopK
Notably, the control LASSS treatment ( bar 10 , missing HGF) exhibited a low activation index equivalent to the baseline level ( bar 1 in the left column), indicating that LASSS does not, itself, stimulate c-met signaling directly
Studies suggest that specific probiotics can increase GLP-1 levels, which may help support appetite regulation and post-meal blood sugar control
In IBD, some probiotic formulations have shown potential for maintaining remission in mild-to-moderate UC, whereas their efficacy in CD appears more limited [428, 429]
The compulsive or addictive components of primary polydipsia may therefore be targeted by GLP-1 RAs
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