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Glutathione is a required substrate for a family of enzymes called glutathione S-transferases, which conjugate glutathione to reactive compounds including drug metabolites and environmental toxins making them water-soluble for excretion

10.1093/humrep/deq220 240 WonJ

This is mediated predominantly via CYP3A4/5, with minor contributions from CYP1A2 and CYP2B6

Three SAM molecules are required for the methylation of phosphatidylethanolamine to phosphatidylcholine by phosphatidylethanolamine N-methyltransferase (PEMT)

Higher concentrations may increase results but also increase irritation risk

benthamiana conferred elevated resistance to bacterial and fungal infections