Effect of the GLP-1 receptor agonist semaglutide on metabolic disturbances in clozapine-treated or olanzapine-treated patients with a schizophrenia spectrum disorder: study protocol of a placebo-controlled, randomised clinical trial (SemaPsychiatry)
Participants randomized to orforglipron initiated treatment with 1 mg once daily and increased the dose every four weeks until reaching the randomized dose of 3 mg, 12 mg or 36 mg
While the exact mechanisms remain unclear, these pathways are thought to play a role in appetite regulation and energy balance
The approach involves regular monitoring and support to ensure adherence and effectiveness
Synthesized to 99% purity, with every lot supported by an independent Janoshik COA and full batch traceability
While taking CONTRAVE, you or your family members should pay close attention to any changes, especially sudden changes, in mood, behaviors, thoughts, or feelings