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Because its designed to hold up well in the digestive system, it doesnt require special timing

Inhibition of acid sphingomyelinase reduces reactive astrocyte secretion of mitotoxic extracellular vesicles and improves Alzheimers disease pathology in the 5xFAD mouse

(2021) 10(1):e017752

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This chelation function is particularly important given the ubiquitous nature of heavy metal exposure in modern environments