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Stopping treatment too soon : Quitting GLP-1 therapy often leads to rapid weight regain
Prescribing information: Ozempic (semaglutide) injection, for subcutaneous use
GLP-1 receptor agonists activate the GLP-1 receptors located in the hypothalamus in the brain, which regulates food intake
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We find that semaglutide in male mice prevents brain infiltration of neutrophils, excessive cytokine release, and suppresses neuroinflammation-associated transcriptional signatures specifically in microglia, endothelial cells, and a subset of pericytes
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