Injections are often discussed for more targeted tissue support, while capsules may be reviewed for convenience or digestive-related concerns
Participants over 55 responded nearly as well as younger cohorts, suggesting the mechanism works effectively regardless of age-related metabolic changes
The ADDITION-PRO study was funded by an unrestricted grant from the European Foundation for the Study of Diabetes/Pfizer for Research into Cardiovascular Disease Risk Reduction in Patients with Diabetes (74550801), by the Danish Council for Strategic Research and by internal research and equipment funds from Steno Diabetes Center
There have been six publications to date that consider the results of the SELECT trial, none of which calculate a NNT, either for the primary or composite endpoints [21, 34,35,36,37,38]
Discussion In the primary analyses of the global PIONEER trials, oral semaglutide consistently demonstrated clinically meaningful reductions in HbA 1c and body weight across a broad spectrum of patients with T2D [7,8,9,10,11,12,13,14]
This marks a significant milestone, indicating that non-invasive eye drops can offer comparable benefits to existing injectable therapies for dry AMD