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In a phase 2 study, comparing the results of the empagliflozin arm to the control arm showed a significant improvement in the electrophysiological studies and a significant decrease in the pain score and the mean serum levels of neuron-specific enolase and malondialdehyde in patients with DPN
Pharmaceuticals (Basel) 2019, 12: E8
They purchase bulk active ingredient from API manufacturers rather than producing it themselves
MEDI0382, a GLP-1/glucagon receptor dual agonist, meets safety and tolerability endpoints in a single-dose, healthy-subject, randomized, phase 1 study
The role of aberrant mitochondrial bioenergetics in diabetic neuropathy