tirzepatide elevated liver enzymes Is Hard on Liver? Safety and Benefits Explained Eli Lilly's Zepbound improved liver

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Due to the rapid renal clearance of small peptides like GLP-1, along with its deactivation by dipeptidyl peptidase 4 (DPP4), development of stable peptides, with an increased resistance to DPP4 was required (4)

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Common side effects include mild nausea (most pronounced after injection days), constipation, and occasional appetite suppression discomfort

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More research is still needed to understand the role this medication could play as a potential preventive therapy for high-risk patients