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Vitamin B12 Q&A Vitamin B12 injections are supplementary shots that help treat deficiencies in vitamin B12

The ACG Clinical Guidelines for Crohns Disease Management stratify therapy by disease severity and location

This can cause methyl trapping, where the excess methylfolate is unable to be utilised in the methionine cycle (through the MTR enzyme) as usable B12 levels are too low

Both support healing but through different mechanisms

Specific Indications for Combined Therapy Tiaminal B12 injection is for people with both thiamine and cobalamin deficiencies

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