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Direct injection of 1 nmol GLP-1, exendin-4, or liraglutide to the ARC significantly suppressed food intake and body weight, with the effects observed over the 24 hours following injection [71,79,80]
This study was partially supported by the Brazilian National Council for Scientific and Technological Development (CNPq) (grant number 402626/2012-5)
3) Lu, Shelly C
[4] A major double-blind study (17,604 participants) showed semaglutide (Wegovy) reduces major adverse cardiovascular events by 20% in adults with overweight/obesity and established cardiovascular disease, but without diabetes
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