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ARC, arcuate nucleus of the hypothalamus

This short peptide chain has been identified in preclinical research as the region of the hGH molecule responsible for its fat-metabolizing properties while being structurally isolated from the regions associated with cell proliferation, glucose dysregulation, or insulin resistance

doi: 10.1016/j.euroneuro.2017.10.032 5 BarnesN

Activation of AMPK and inactivation of Akt result in suppression of mTOR-mediated S6K1 and 4E-BP1 pathways leading to neuronal cell death in in vitro models of Parkinsons disease

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Neurosci Lett 52:S18 Li X, Zhang C, Zhang X et al (2015) An acetyl-l-carnitine switch on mitochondrial dysfunction and rescue in the metabolomics study on aluminium oxide nanoparticles