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This site audits what the peer-reviewed literature actually contains, what regulators have said, and where the limits of the data lie

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Yes, refrigerating an opened vial at 2 to 8C is acceptable and will not damage it

And the only condition they were even considering it for was ulcerative colitis

When HSPs successfully restore protein homeostasis, the cell may enter the repair and survival pathways, and when cellular damage exceeds the compensatory threshold, cell death pathways are activated (Somero and Physiology, 2020)