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Many women avoid bowel movements because they worry about pain or tearing, which can make the problem worse

Two practical habits help: drink between meals (not large amounts during) so liquid does not stretch your stomach faster than food and trigger early fullness, and pay attention to electrolytes sodium, potassium, magnesium especially on days with GI symptoms or if your clinician recommends them

And some people cant tolerate these drugs because it gives them just too much distress

Experimental evidence indicates that the ability of enterostatin to regulate fat intake involves the process of thermogenesis (regulated energy consumption for heat generation) and the reward circuitry of the central nervous system

Below: simple to deep

The Annals of Pharmacotherapy , 46 (2), 240247