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It is worth to mention that available reports describing the encapsulation of GSH- or albumin-protected AuNCs are limited to hydrophilic, rather than hydrophobic, matrices such as nanogels 25 , aqueous core of microcapsules 26 , silica nanoparticles, protein nanoparticles 27,28 , polymer nanoparticles 29,30 and metal-organic frameworks 31
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The problem is not the molecule it is the delivery architecture, and liposomal glutathione for skin brightening exists precisely to solve that structural gap
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Mild flushing or warmth shortly after dosing
de Ligny et al
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