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Extended-release berberine at 1000mg twice daily is an alternative that provides similar total daily exposure with fewer dosing events and often better GI tolerability

At the same time, efforts should also be made to correct related metabolic abnormalities

Outcomes depend on correct dosing, lifestyle support, and consistent follow-up, making provider-guided treatment more important than the name on the prescription

J Clin Endocrinol Metab (2020) 105:e27106

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The early stages of fatty liver disease usually do not produce any symptoms, although some may have fatigue or a dull pain in the right upper abdomen