Methylcobalamin is the bioactive form of vitamin B12, meaning it doesn't require the liver conversion step
This 8-week schedule escalates by ~100 mcg weekly
But I think what's really cool is that especially over the past few years, there's been this big shift into broadening the scope of what maybe had been traditionally considered part of a reimbursement style program
Select the site that seems the most convenient for the first-time injection and alternate the location every week to avoid injection-site reactions
The Two Components: Different Mechanisms, Complementary Roles To understand why the ratio matters, the two components need to be understood separately first
Injection-Related Risks With Injectable GHK-Cu FDA identifies compounded injectable drugs containing GHK-Cu as a potential immunogenicity risk because of aggregation and peptide-related impurities, and FDA notes limited human data to inform safety considerations [8]