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The rate of weight loss may influence menstrual disruption
doi: 10.1186/s12944-023-01867-3 39
Data from a sub-study of the STEP 1 clinical trial indicates that approximately 40% of the weight lost on semaglutide can be lean mass (muscle and bone) without targeted interventions (Wilding et al., 2021)
That older content may have been accurate before December 2025
Patients and clinicians should nonetheless remain alert to this possibility, particularly given the substantial weight loss retatrutide has produced in phase 2 trial settings (see the New England Journal of Medicine , 2023)
Contacts Bailey Wray anthonyBarnum Public Relations [email protected] 318.470.5403 This release was updated in October 2024 to reflect the latest regulatory news.
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