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A person starting at 350 pounds may lose 70 pounds (20%) while a person starting at 200 pounds loses 40 pounds (20%)
Heartburn and acid reflux can worsen because stomach acid has more time to irritate the esophagus when the stomach empties slowly
A 16-week phase 1 trial for the oral formulation reports a mean weight loss of 13% in the treatment group, compared to 1% for placebo (82)
No membership fees apply, making it an accessible option for personalized cholesterol management
Some research shows it could benefit heart function, though evidence is mixed
Although overall utilization remains below 1 percent of eligible adolescents, a marked increase in adoption was observed in 2023
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