GI symptoms: Record nausea, bloating, constipation, or diarrhea with severity (mild, moderate, severe) and duration
How Your Body Adjusts As your appetite resets, youll naturally eat smaller portions and feel full faster
Neither of these scenarios means GLP-1 medications are off limits
Private Insurance Coverage of Obesity Medications in Canada: 2025 Survey Results
And the short, evidencebased answer to can you split tirzepatide doses? is no, you should not split your tirzepatide injection on your own
What the Clinical Data Actually Shows The most definitive comparison comes from the SURMOUNT-5 trial, a direct head-to-head study published in the New England Journal of Medicine comparing tirzepatide 10 mg and 15 mg against semaglutide 2.4 mg in adults with obesity but without diabetes