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Phase 3 trials currently underway Seven TRIUMPH trials are testing retatrutide across multiple indications: TRIUMPH-1 : Obesity without diabetes TRIUMPH-2 : Type 2 diabetes TRIUMPH-3 : Obesity with type 2 diabetes TRIUMPH-4 : Obesity with knee osteoarthritis (COMPLETED, 28.7% weight loss) TRIUMPH-5 : Obstructive sleep apnea TRIUMPH-6 and 7 : Additional indications These trials will provide the definitive data for the commercial dosage chart
The initiation dose is sub-therapeutic
It seems that obesity plays an important role in the pathophysiology of migraine as well, with obese women having elevated plasma levels of calcitonin gene-related peptide (CGRP) compared to controls [32, 33]
Before considering any incretin-based medicine, prepare a clear medication list, weight and glucose history, prior pancreatitis or gallbladder history, thyroid cancer history, pregnancy plans, and previous side effects from similar drugs
doi: 10.20517/2394-4722.2019.008 334
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