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Cell death at this time point was indiscriminate, as the lesion site was largely devoid of neuronal (NeuN + ), astrocytic (GFAP + ), oligodendrocyte (APC + ), and microglia (Iba1 + ) staining (all in green)
Some patients may experience mood changes or anxiety, which could be related to changes in eating patterns, blood glucose levels, or direct pharmacological effects
It also helps make neurotransmitters (messenger cells) and the hormones serotonin and norepinephrine
The most commonly reported adverse effects were mild to moderate headache and gastrointestinal symptoms including diarrhea, flatulence, nausea, and increased appetite
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However, the authors of the latter study emphasized the need for further studies to draw more definitive conclusions
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