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The molecular events leading to activation or silencing of glucose-sensitive neurons are surprisingly similar to those of the endocrine pancreas and include neuronal uptake of glucose via GLUT2, conversion to pyruvate (and finally ATP) via glucokinase, and modulation of neuronal firing mediated by changes in K ATP channel activity, cell depolarisation and Ca 2+ influx

Start your intake How Temperature Affects GLP-1 Peptide Stability GLP-1 peptides are sensitive to heat and light because their amino acid chains denature when exposed to temperatures above 30C (86F)

Kiernan et al

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