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This includes individuals with medical conditions such as pernicious anemia, atrophic gastritis, celiac disease, or Crohns disease, all of which can interfere with B12 absorption

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Because it acts through the same receptor as ghrelin, experimental models have repeatedly shown links to changes in hunger signaling, energy intake, and neuroendocrine responses to food

These may warrant urgent referral to neurology or haematology services

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Manufacturers specify shelf life at -20C ranging from 12 to 24 months, though peptides stored under these conditions often retain activity beyond labeled expiration if the seal remains intact