Blood sugar management is your primary concern
For example, certain antidepressants, antipsychotics, and corticosteroids may cause weight gain as a side effect
However, the simultaneous GLP-1 and GIP agonism appears to counterbalance this effect while still allowing glucagon to drive its metabolic benefits
Glucagon-like peptide 1 receptor agonists known as GLP-1 such as semaglutide and tirzepatide are a class of medications developed to treat diabetes and obesity
Further to the above, physiological processes that degrade ROS are known to be impaired in neurodegenerative diseases and as a consequence of aging
Larger, prospective, controlled studies with standardized outcome adjudication are required to better define the safety and clinical impact of semaglutide in patients with ESRD