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Supplementation with an olive oil rich diet (G1-P21) [132], a highly palatable food diet in females (P28-65) [133], a highly palatable food diet in both sexes (P20-84) [134] or a HFD in males (P20-84) [135] reversed the POS-induced depressive-like behavior in the FST in males at P80-87 [132] and at W10-12 [134] and in females at P54-59 [133], and in the SPT in males at P34-84 [135]
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10.7554/eLife.33710 eLife 11 CorkS
Nonclinical Toxicology 13.1 Carcinogenesis, Mutagenesis, Impairment of Fertility In a 2-year carcinogenicity study in CD-1 mice, subcutaneous doses of 0.3, 1 and 3 mg/kg/day [9-, 33- and 113- fold the maximum recommended human dose (MRHD) of semaglutide tablet 14 mg, based on AUC] were administered to the males, and 0.1, 0.3 and 1 mg/kg/day (3-, 9- and 33-fold MRHD) were administered to the females
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