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Although some of these correlations persist across disease or medication status, others appear to be lost among FENNS suggesting that steady formation of the antioxidant uric acid (UA) via purine catabolism is altered early in the course of illness

153 Complementing MDR1-mediated drug efflux, the multidrug resistance-associated protein (MRP) subfamily comprises nine members (MRP19) that confer resistance through partially distinct yet overlapping mechanisms

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