Semaglutide Brand names: Ozempic, Wegovy, Rybelsus How it works: Semaglutide is a so-called GLP-1 drug: a hormone mimicker meant to treat type 2 diabetes
The Gila monster version Eng isolated exendin-4 lasted for hours because the lizard, which eats only a few times a year, evolved a hormone that could hang around and squeeze every calorie out of a rare meal
Common Side Effects water retention or puffiness increased appetite fatigue or daytime sleepiness headaches nausea or dizziness redness or irritation at the injection site These effects are usually manageable and often improve as the body adjusts or as dosing is refined under medical supervision
doi: 10.1210/jcem.78.5.8175987 69 Kautzky-WillerAThomasethKPaciniGClodiMLudvikBStreliCet al
Novel thyroxine formulations: a further step toward precision medicine
The gene expression of the antimicrobial peptide regenerating islet-derived protein 3 gamma (RegIII) was reduced in the jejunum and colon of HFD-fed wild-type mice, but not in HFD-fed MyD88 knockout mice (124)