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About one-third of participants achieved 20% or greater weight loss, while some achieved less than 10%

In practical terms, a 95 kg person with 30% body fat who maintains a 400-calorie daily deficit might lose 5-6 kg total over 12 weeks through diet alone

They intended to follow patients for 24 weeks but due to the COVID-19 pandemic, this was not possible

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[18] FDA identified limitations in characterization data, potential immunogenicity concerns for injectable use, limited information for proposed routes, lack of established effectiveness for obesity, and insufficient long-term safety information