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Immediately, a wave of concern hits

Biochemically, ferroptosis involves iron dysregulation, ROS accumulation, mitochondrial dysfunction, glutathione (GSH) depletion, and lipid peroxidation (Liu et al., 2025)

The resulting consensus provides an integrated synthesis of available evidence, incorporating data from RCTs, systematic reviews, meta-analyses, in vitro , and animal studies

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Additional findings indicate that the peptide may reduce tissue injury caused by exposure to non-steroidal anti-inflammatory drugs, highlighting its potential involvement in protective responses against inflammation-related damage (8)

[5] Applied topically, it works at the dermal level , the deeper structural layer where collagen, elastin, and glycosaminoglycans are produced