The drugs are now covered only for patients with a body mass index over 40
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Tirzepatide, sold under the brand names Zepbound and Mounjaro, is available in U.S
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The self-association of -syn through the hydrophobic face of the NAC domain, which is autoinhibited by the interaction between the N- and C-terminal domains, is important for LLPS and the subsequent liquidgel/solid transition at high concentrations of -syn alone in vitro (Sawner et al, 2021)
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